Publication Title Effect of honey on some biochemical parameters in the brain tissues of Wistar rats exposed to cadmium. Download PDF
Publication Type journal
Publisher Uniport Journal of Engineering and Scientific Research (UJESR)
Publication Authors Diakparomre, Ovovwe; Onyeukwu, Onyeka Benjamin; Asagba, Samuel Ogheneovo
Year Published 2023-10-27
Abstract Cadmium (Cd) toxicity has led to the search for possible ameliorators, which is an interesting area of research currently being explored worldwide. This research investigated the effect of honey on some biochemical parameters in the brain tissues of rats following acute and sub-chronic Cd exposures. Thirty adult Wistar rats were divided into 6 groups (A-F): control, sub-chronic Cd exposure, sub-chronic Cd exposure plus honey, acute Cd exposure, acute Cd exposure plus honey and honey only, respectively. Cadmium chloride (CdCl2) was administered at a dosage of 2 mg/kg body weight by intraperitoneal injection (IP), every two days interval, for a period of 4 weeks (for the sub-chronic study) and a dosage of 4 mg/kg body weight by IP, 12 hours before sacrifice (for the acute study). Honey was administered at a dose of 1 ml/kg body weight orally, once daily for 4 weeks. The study revealed that groups B and D showed significantly higher lipid peroxidation and acid phosphatase (ACP) activity in the brain tissues than that of group A; as well as significantly lower catalase (CAT), superoxide dismutase (SOD), alanine aminotransferase (ALT), aspartate aminotransferase (AST) and alkaline phosphatase (ALP) activities. However, administration of honey to Cd-exposed rats ameliorated the Cd-induced changes by causing a reduction in lipid peroxidation and maintaining the activities of these enzymes in the brain tissues within levels significantly similar to that of the control group. This suggests that honey produces an ameliorative effect on Cd-induced injuries in the brain tissues at acute and sub-chronic levels.
Publication Title Microbiological Assessment of WellWater Obtained in Burutu Town, Delta State, Nigeria Download PDF
Publication Type journal
Publisher Continental J. Biological Sciences
Paper Link doi:10.5281/zenodo.3820667
Publication Authors Okiriguo Vivian Ifeoma and Diakparomre Ovovwwe
Year Published 2019-08-30
Abstract This study was carried out to assess the microbial quality of ground water sources (well water) in Burutu town. Five randomly selected wells from five(5) areas of the town were selected and water samples obtained. The samples were subjected to standard methods of analysis. The results showed that the total coliform present in the water samples ranged from 2204 cfu/100ml to 2477 cf/100ml. These values are far above the World Health Organization (WHO) standard of 0cfu/100ml (absence of coliform) for safe potable water. These values may be as a result of poor groundwater source (well) construction, poor handling and lack of maintenance. Individuals who utilize water from these wells for consumption and domestics purposes are at risk of contacting water borne diseases if not properly treated before use.
Publication Title Diagnostic ratios of polyaromatic hydrocarbons for the identification of pollution sources in clams from Okwagbe, Delta State Nigeria Download PDF
Publication Type journal
Publisher Science World Journal
Paper Link https://dx.doi.org/10.4314/swj.v19i2.30
Publication Authors Umudi E.Q., Umudi O.P., Igere O.F. and Diakparomre O.
Year Published 2024-07-05
Abstract Polyaromatic hydrocarbons (PAHs) are pollutants found in the environment. Their sources are anthropogenic and natural. Since clams are filter feeders, they can accumulate (PAHs) in their tissues providing vital tool for pollution source monitoring. This study investigated different pollution sources using diagnostic ratio of PAHs. Clams were collected from Okwagbe River, Delta State, Nigeria and analyzed for their polyaromatic hydrocarbon (PAH) contents. The sixteen (16) priority PAHs, including: 1-methylnaphthalene and 2-methylnaphthalene were determined in flesh and shells using gas chromatography. A mixture of acetone/dichloromethane/n-hexane was used for the Soxhlet extraction. The concentration of mean total PAHs was 2.495 ?g/kg for flesh and 2.156 ?g/kg for shell. The benzo(a)pyrene (B[a]P) of flesh was 0.210 ?g/kg and 0.312 ?g/kg for shells. These valves did not exceed the permissible limit of 6.0 ?g/kg for benzo(a)pyrene and 35.0 ?g/kg for PAHs. The isomeric ratio was used to find the sources of PAHs in flesh and shells. It showed the sources were petrogenic, pyrogenic and wood burning. Clams can be a tool for tracking pollution source identification and improve understanding of human activities on ecosystems.
Publication Title Amelioration of Cadmium-Induced Biochemical Alterations in Heart Tissues of Wistar Rats Using Bee Honey Download PDF
Publication Type journal
Publisher Tropical Journal of Natural Product Research
Paper Link https://www.tjnpr.org
Publication Authors Ovovwe Diakparomre, Onyeka B. Onyeukwu, Samuel O. Asagba
Year Published 2024-08-01
Abstract The hunt for potential remedies for cadmium (Cd) toxicity is an exciting topic of research that is now being investigated globally. This study investigated amelioration of cadmium-induced biochemical alterations in heart tissues of Wistar rats using bee honey. Six groups (1–6) of thirty adult Wistar rats were used for the study: control, sub-chronic Cd exposure, sub-chronic Cd exposure plus honey, acute Cd exposure, acute Cd exposure plus honey, and honey only. For the sub-chronic investigation, Cd chloride (CdCl2) was injected intraperitoneally (IP) at a dose of 2 mg/kg body weight every two days for a period of four weeks, and for the acute trial, a dose of 4 mg/kg body weight was injected IP 12 hours prior to sacrifice. 1 ml/kg of body weight of honey was given orally once every day for four weeks. According to the study, groups 2 and 4 had substantially greater levels of lipid peroxidation and acid phosphatase (ACP) activity in the heart tissues compared to group 1. Catalase (CAT), superoxide dismutase (SOD), alanine aminotransferase (ALT), aspartate aminotransferase (AST), and alkaline phosphatase (ALP) enzyme activity were also significantly decreased. This study shows that honey treatment significantly ameliorates Cd-induced toxicities in heart tissues by suppressing lipid peroxidation and normalizing antioxidant enzyme activity. Further work should be done to identify specific phytochemical antioxidants and its mode of action in ameliorating Cd-induced toxicities in heart tissues.
Publication Title Analysis of the Mineral Nutritional and Phytochemical Composition of Mistletoe Leaves (Loranthaceae) Download PDF
Publication Type journal
Publisher Faculty of Natural and Applied Sciences Journal of Applied Chemical Science Research
Paper Link www.fnasjournals.com
Publication Authors Umudi, E.Q., Umudi, O.P., Diakparomre, O., Obiagwe, J., & Nwakwanogo, B.E.
Year Published 2024-09-01
Abstract Medicinal plant extracts have been used in different cultures, for treating ailments and managing health issues like inflammatory conditions, hypertension, diabetes mellitus, arthritis, epilepsy, etc. Extracts of mistletoe leaves were studied for their mineral, nutritional and phytochemical composition. The proximate analysis results reveal high fibre content (11.1%) and low fat (3.2%) content, making it a good cholesterol-lowering agent. The mineral composition revealed that mistletoe leaves are nutritionally beneficial as they contain relatively high levels of iron, calcium, potassium, manganese and magnesium, which all play important physiological and metabolic roles in the body. The Na/K and Ca/P ratios of 0.623 and 3.931 respectively are considered favourable, making the leaves nutritionally and physiologically important. The presence of tannins, saponins, flavonoids, steroids, resins and alkaloids could be responsible for their use in traditional medicine. These findings therefore reveal that mistletoe leaves can be utilized as medicinal/curative agents in ameliorating health-related issues such as hypertension, cancer, arthritis and fertility-related ailments; as well as being nutritionally beneficial, if properly harnessed.
Publication Title Treatment of Tannery Effluent from Sharada Industrial Estate in Kano, Nigeria with Porous Clays Download PDF
Publication Type journal
Publisher Caliphate Journal of Science & Technology (CaJoST)
Paper Link https://dx.doi.org/10.4314/cajost.v6i3.6
Publication Authors Ese Q. Umudi, Ogheneyoma P. Umudi, Okeoghene F. Igere and Ovovwe Diakparomre
Year Published 2024-12-09
Abstract The tannery industry plays a significant role economically, but it negatively hampers the environment by elevating the concentration of pollutants during the tanning process. The geochemical and mineralogical properties of two Nigeria clay samples were studied by Atomic Absorption Spectrophotometer (AAS) and X-ray diffractometer respectively. Clay samples were obtained from Ozanagogo and Otor-Edo in Delta State, coded OZ and OT respectively. Column clay packed with pebbles in a ratio of 1:4 was used for the purification/removal of pollutants using batch method. Results revealed that the pH of the treated effluents increased from 3.7 to 6.9 and 8.2. Turbidity values reduced from 63.00 NTU to 0.2 NTU and 0.5 NTU, while COD values dropped from 877.00 mg/L to 2.71 mg/L and 15 mg/L, and BOD values decreased from 350.00 mg/L to 0.71 mg/L and 5.00 mg/L. A reduction in chloride levels from 2650.00 mg/L to 97 mg/L and 102.00 mg/L was also observed, while treatment of the effluents brought the bacterial count from 1.9x108 to nil, using both clay samples. The mineralogical study revealed that kaolinite was the most abundant clay mineral in both clay types, while hematite was the least abundant in both samples. This paper studied the use of locally sourced material (clays) in treating tannery effluent, and compared the values of the treated effluent with WHO, SON and NESREA standards for drinking water. This study has shown that the porous clay method is an effective purification system using cost-effective, locally sourced materials and a simple decentralized treatment method.
Publication Title Palm Wine: A Review on Its Composition, Preservation, Health Benefits, and Market Value Download PDF
Publication Type journal
Publisher International Journal of Basic Science and Technology
Paper Link https://doi.org/10.5555/PRNM1680
Publication Authors Onyeukwu, O. B., Diakparomre, O., Njideaka, O. T., Dibie, D. C. and Nwaiku, F.
Year Published 2024-04-05
Abstract Numerous people in sub-Saharan Africa, Asia, India, and Mexico enjoy palm wine, a traditional alcoholic beverage made from the sap of various palm plants. Its colouring is pale, and its flavours run the gamut from sweet to sour and vinegary. For people who live in cities and villages, tapping the palm tree to get the beverage is an important source of income. Although the alcohol concentration of fresh palm wine is low and it is sweet, it gradually rises through fermentation. It is used for numerous purposes, most notably for medicine, weddings, and traditional naming rituals. They are suitable for improving vision since they contain vital microbes like yeast as well as nutritionally significant ingredients like amino acids, proteins, vitamins, minerals, sugars, alcohols, and water. Jaundice, smallpox, chicken pox, measles, and malaria have all reportedly been treated with palm wine. Additionally, palm wine assists nursing mothers produce more milk in addition to its reputed antioxidant qualities. The purpose of this study is to review palm sap/wine, its preservation, applications, biochemical components, odorants, microbiota, nutrient content, and health effects. It also conducts an economic analysis of the palm wine market and traditional fermentation and distillation of raphia palm sap for ethanol production.